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KMID : 0379520020180040397
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한국독성학회지
2002 Volume.18 No. 4 p.397 ~ p.400
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Acute Oral Toxicity of G. bimaculatus in Rats
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Kim In-Sun
Ahn Mi-Young
Ryu Kang-Sun
Lee Byung-Mu
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Abstract
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This study was carried out to investigate the acute toxicity of G. bimaculatus in Sprague-Dawley rats. G. bimaculatus was administered orally at doses of 8, 40, 200, 1000 and 5000 mg/kg. in this study, number of deaths, clinical sign, body weights, and pathological examination were investigated for 14 days after administration of G. bimaculatus. The results indicate that G. bimaculatus did not show any toxic effect in rats and oral LD_{50} value was over 5000 mg/kg in Sprague-Dawley rats.
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KEYWORD
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Acute toxicity, G. bimaculato, LD_{50}values, Pathological examinations
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